RENOPROTECTIVE EFFECT OF LEFLUNOM1DE AGANIST ISCHEMIA-REPERFUSION INJURY IN RATS
نویسندگان
چکیده
منابع مشابه
Renoprotective effect of crocin following liver ischemia/ reperfusion injury in Wistar rats
Objective(s): The objectives of the current study were to evaluate the effects of hepatic ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and histopathological changes in rat kidney, and to investigate the effect of crocin on IR-related changes. Materials and Methods: Thirty-two male Wistar rats were randomly allocated into four groups (n=8). The...
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Introduction: Acute kidney injury (AKI) has been known as a complex clinical complication in diabetic patients. The main cause of AKI is ischemia/reperfusion injury (IRI). This study was designed to investigate the protective effects of GABA on renal IRI in hyperglycemic female and male rats. Methods: Sixty STZ induced diabetic male and female Wistar rats were categorized in 10 groups (5 fem...
متن کاملRenoprotective effect of crocin following liver ischemia/ reperfusion injury in Wistar rats
Objectives The objectives of the current study were to evaluate the effects of hepatic ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and histopathological changes in rat kidney, and to investigate the effect of crocin on IR-related changes. Materials and Methods Thirty-two male Wistar rats were randomly allocated into four groups (n=8). They wer...
متن کاملMechanisms underlying the renoprotective effect of GABA against ischemia/reperfusion-induced renal injury in rats.
The excitation of the renal sympathetic nervous system plays an important role in the development of ischemic acute kidney injury (AKI) in rats. We have reported that intravenous treatment with GABA has preventive effects on ischemia/reperfusion (I/R)-induced renal dysfunction with histological damage in rats. However, detailed mechanisms of the action of GABA on the renal injury were still unk...
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Objective- This study investigated the effect of amlodipine on intestinal ischemia-reperfusion injury in ratsDesign-Experimental studyAnimals-Fifteen male Sprague-Dawly rats weighing 200-220gProcedure- Rats were randomly divided into 3 groups: IR group (operation with clamping), sham group (operation without clamping), and IRA group (operation with clamping and 5mg/kg amlodipi...
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ژورنال
عنوان ژورنال: Mansoura Medical Journal
سال: 2006
ISSN: 2735-3990
DOI: 10.21608/mjmu.2006.128756